Bramante Staircase is the name given to two staircases in the Vatican Museums in the Vatican City State: the original stair, built in 1505, and a modern equivalent from 1932.

The modern double helix staircase, also in the Pio-Clementine Museum, and commonly referred to as the "Bramante Staircase", was designed by Giuseppe Momo in 1932 and was inspired by the original Bramante Staircase. This staircase, like the original, is a double helix, having two staircases allowing people to ascend without meeting people descending; as with the original, the main purpose of this design is to allow uninterrupted traffic in each direction. It encircles the outer wall of a stairwell approximately fifteen meters wide and with a clear space at the centre. The balustrade around the ramp is of ornately worked metal. A canopy located above provides the necessary light to illuminate the stairs. The staircase is located at the end of the museum visit and all visitors leave by this route.